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Top 6 Best pet urine neutralizer for dogs and cats

There is a completeness and fulfilment that pets bring into our lives that we cannot replace with anything else. We, in return, have to share our living space with these cuddly sweet companions. This includes cleaning after them, which can be challenging at times.

If you have new pups that are yet to be housetrained, their pee on your carpets and rugs can leave your house with an undesirable stench that’s hard to get rid of. You also might end up with stains on delicate fabrics around the house. This is where a specially formulated urine neutralizer comes in handy when compared to general household cleaners.

There are a variety of pet urine neutralizers on the market but to get one that does the job just right is not as easy. In this guide, we have put together a list of the 6 best dog urine neutralizers for you to choose from and outline the pros and cons of each.

Let’s go through the list and see how they compare but before we do, let’s tell you why the Simple Solution Extreme Pet Stain and Odor Remover is our best overall pick. It has active ingredients, pro-bacteria, and enzymes, that break down odours and stains at the molecular level. It also has a 3 times stronger formula in comparison to the regular version of the neutralizer, which makes it much more effective. This neutralizer works to clean a pet’s vomit, urine, and poop off carpets, rugs, artificial grass, and a variety of other surfaces. It comes with a multi-functional sprayer bottle, that’s a nice touch to it all.

Best Pick

Simple Solution Extreme Pet Stain and Odor Remover
Our best pick is the Simple Solution Extreme Pet Stain and Odor Remover. It uses pro-bacteria and enzymes to clean pet urine, vomit, and poop off carpets, rugs, upholstery, and a host of other surfaces. This ensures that ordos are eliminated at the source. The best part about it is that you can either choose the scented version or the plain one. It comes with a multi-functional bottle, which makes the application easy on different surfaces as you can choose between spray types. It works best when used straight away so this is what we recommend it for and it does an excellent job and its easy to see why it's such a popular choice.


Prokleen 5L Multi-purpose Deodorizer
Our runner-up is the PROKLEEN 5L Multi-purpose Deodorizer. It’s a great alternative if you are looking for a neutralizer that not only neutralizes pet urine but also performs other functions like sanitizing and deodorizing and using outdoors. It’s ideal if you are looking for a neutralizer that works effectively both indoors and outdoors. It works great if you have artificial grass too. Aside from pet messes, this neutralizer will work on virtually any other stain, which makes it a versatile product. It's the perfect cleaner for use around your home if you want one wholesome cleaner. Another big advantage is that because its a concentrate and you have to mix it with water and spray it on, you can choose between 3 concentrate levels depending on how soiled the area is. It's also more affordable because its a concentrate but you do need a spray bottle to spray it on with.

Best Pet Urine Neutralizers Reviews

1. Simple Solution Extreme Pet Stain and Odor Remover

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Simple Solution Extreme Pet Stain and Odor Remover

If you just brought a new pup home or perhaps have an older dog, you will need a strong stain remover for your carpets and any other fabrics around your house if your house is to retain its good looks. This is one of the best pet urine neutralizers you will find on the market currently. It does not only work on urine odor but also works on vomit and pet poop, leaving your house fresh and also preventing repeat marking by the pet. What we will say is that its works best when used straight away, for older stains there are better options but if you want a ready to use spray just in case of any accidents, then this is a great choice.

It is 3 x strong as the original simple solution odour remover we use to recommend, and it also features a formula with both biodegradable enzymes and pro-bacteria that break down stains and odors. This ensures that the neutralizer gets rid of pathogenic microbes from the pets bodily fluids. This stain remover will clean both new and old stains off surfaces around your home but it works much better on new stains when used straight away. People have has mixed results when using on old stains.

It’s safe for use for pets and kids in case you have small children in the house. You can use this stain remover on any water-safe surfaced as well as fabrics such as rugs, carpets, clothes, bedding, or furniture upholstery which is why it’s a great choice for inside the home as it will treat nearly all surfaces.

The versatile simple solution extreme bottle allows multiple application methods using the spray nozzle. With the foam, you can get rid of tough stains effectively, the stream application method allows you to neutralize odours in hard to reach places like cracks, while with the spray, you can cover a large area. With refill options available, you don’t have to buy a new bottle every time.


  • It is safe for pets and children in case you have little ones in the house.
  • The formula contains pro-bacteria and enzymes that break down the toughest of stains.
  • A multi-functional sprayer on the bottle for different application methods
  • Works on a wide variety of surfaces, rugs, carpets, clothes, and bedding
  • Works on both new and old stains
  • Works on urine, vomit, and poop pet messes, leaving your house fresh and odor-free


  • May not completely get rid of old stains

Why do we recommend it?

This neutralizer’s strong formula is multifunctional and we like that it works on urine, vomit, and poop messes and can be used to treat and clean most household surfaces. The strong formula works on both new and old stains but it’s worthing noting its much more effective when used straight away and that older stains can be difficult to remove. We this in mind we recommend it to simply to have a ready to use spray you can use a moment notice. It is also safe for both pets and kids if applied right which is another important feature we look for.

We love that the bottle sprayer allows for different application methods because of the adjustable nozzle to apply different spray types. This allows you to clean even tough to reach places like crevices on the floor or treat larger areas with a mist spray. This neutralizer, unlike others, is safe to use on synthetic rugs too. It also has numerous positive reviews on Amazon, and that is reassuring. Overall if you looking for a ready to use spray, no concentrate to deal with, then this is probably the best choice overall.

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2. PROKLEEN 5L Multi-Purpose Deodorizer

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PROKLEEN 5L Multi-Purpose Deodorizer

If you are looking for a versatile pet urine neutralizer that’s not only effective with animal stains but suitable for all your other cleaning needs, this is the best one you will find on the market but it does come as a concentrate so there is some mixing involved. It’s multi-purpose too, and when used, it neutralizes odors, sanitizes, and deodorizes, leaving your home fresh and smelling great.

It’s suitable for use on indoor surfaces such as worktops, carpets, upholstery, artificial grass, as well as outdoor uses such as on hard surfaces. You can use it on decks and patios, pretty much anyway where you have issues with stains and odours. With this cleaning agent, you can neutralize urine odours, vomit, smoke, and pet poop in case your dog has a few accidents in the house or outdoors. You can also use it for virtually any other kind of stains, including wine stains so it really is a one fits all solution. It’s safe for home use too, and you can use it on surfaces that come into contact with food.

Unlike other urine neutralizers, this neutralizer is a concentrate that you dilute before application. For the toughest stains, 1 part concentrate with 1 part water will work just fine. If you are dealing with less stubborn stains, a mixing ratio of 1:5 will do. For light stains, go with 1:10 parts of water.


  • Multifunctional, neutralizes, sanitizes, and deodorizes.
  • Works on all kind of stains, smoke, pet urine, vomit, wine, and any other kinds of household stains
  • Works both indoors and outdoor
  • Stronger concentrate formula, you only need to dilute and apply according to the strength of the stains
  • Safe for use on surfaces that come into contact with food
  • Works on carpets, upholstery, artificial grass, and lino flooring


  • Relatively expensive, but it’s to be expected with the strong formula

Why do we recommend it?

Unlike other urine neutralizers that will only deal with pet-related stains, you can use this cleaning agent on virtually any stains. Instead of just getting a urine neutralizer, you get a multipurpose cleaner for all your home cleaning needs.

We love that you can use this neutralizer both indoors and outdoors and that you can alter the concentrate ratio depending on how bad the stain or odour is. This can also help to reduce waste as you can use less concentrate if needed.

It’s also safe to use on surfaces that come into contact with food, which means you can use it to clean your kitchen too. Don’t forget that you do need to get spray bottle whether its an old sprayer bottle from a previous cleaner or you buy a new empty spray bottle, for outdoor use we recommend a garden sprayer.

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3. PRESSED TO FRESH – Pet Urine Odour Eliminator & Neutraliser

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If you are looking for an odour neutralizer that serves as both a cat urine neutralizer and a dog urine neutralizer and is a natural product, then this is the ideal choice for you as its made from cold pressed orange peel. This urine neutralizer utilizes enzymes to get rid of odours by breaking down the bacteria and odours at the source of the odour. This breakdown method works better than other neutralizers that mask odours by deodorizing instead.

It’s made of orange oil, which has neutralizing properties and antibacterial properties. This means the neutralizer also gets rid of any pathogenic bacteria found in animal waste that might be harmful.

It is multifunctional, which means it neutralizes and deodorizes at the same time. This leaves your house odour-free and smelling citrusy in the end.

It has a concentrated formula. You dilute 16ml of this neutralizer with one litre of water. This will go a long way as all you need to do, is put it in a sprayer bottle, spray and wipe away the odours. As dogs don’t like the orange scent, this neutralizer, when used discourages repeat markings by dogs.

This neutralizer works on carpets, upholstery, artificial grass, rugs, and floors. It’s suitable for both indoor and outdoor uses like our runner-up and is safe for both pets and humans.

Since it’s made of organic orange essential oil without artificial chemicals, it is entirely biodegradable. It’s made in the UK too which some people will appreciate.


  • Made of natural materials without artificial chemicals
  • Works both indoors and outdoors
  • Neutralized any pet odours
  • Safe for both pets and humans
  • Uses enzymes to break down bacteria and anything else that might be causing the odours
  • Multifunctional, neutralizes odours and deodorizes
  • Will last a long time as its a concentrate


  • The top covering the bottle tends to leak if not stored right.

Why do we recommend it?

If you have both cats and dogs in your house and you need a natural neutralizer that works for both, this is an ideal option for you. We love that there is no artificial chemical used to make this neutralizer, which makes it safe for both pets and humans.

It can be used both indoors and outdoors and works on carpets, rugs, and artificial grass. It’s multifunctional as it neutralizes odours and deodorizes, leaving a nice citrusy scent behind. At first, it does seem expensive but when you mix such as smaller amount as the concentrate is strong, it will last a long time so still offers excellent value for money, plus it actually works unlike a lot of option out there.

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4. The Chemical Hut 5L Professional Urine Neutraliser Concentrate

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The Chemical Hut 5L Professional Urine Neutraliser Concentrate

This is another urine neutralizer that gets the job done and comes in a concentrate. It works on all pet-related stains like pee, poop, and vomit. It breaks down crystalized waste and turns it into a suspension so that it can be removed and discarded.

It can be used on carpets, rugs, upholstery, and any other surfaces you can clean with water.

Unlike some neutralizers that only neutralize odors, this one also deodorizes, leaving your house clean and smelling good. Makes living with pets easy, fun, and stain free. It’s suitable for cleaning dog messes, cats, or any other pet you have in your household but it can also be used outdoors.

You get an economical 5-litre container when you buy this neutralizer, which will last you for longer.


  • Works on vomit, urine, and poop messes
  • Breaks down crystalized waste into a suspension so that you can easily clean them away
  • Works on upholstery, carpets, rugs as well as outdoor surfaces including decking, patios and artificial grass
  • Comes in an economical 5-litre container which lasts for a long time
  • Can be used to clean all surfaces that you clean with water

Why do we recommend it?

We like that this neutralizer works on cat and dog wastes like vomit, pee, and poop and can used both indoors and outdoors. If you have both these pets, or any other pet for that matter, then this is a fantastic concentrate that works wonders.

Carpet and rug pet messes are the hardest to clean. We like that this neutralizer makes cleaning stains and odours off carpets and rugs easy. We also love that this neutralizer neutralizes and deodorizes, which are two different functions. Overall if you have tried several other products without success this should certainly do the trick. We would describe this as more of a commercial-grade product without the fancy marketing and colourful containers you see with products aimed at the general public.

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5. Dirtbusters Pet Artificial Grass Cleaner

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Dirtbusters pet artificial grass cleaner

This product does a perfect job cleaning stains and neutralizing odours on artificial grass so if you’re looking for a solution primarily for fake grass, this is well worth considering. Environment friendly, dog, and child-safe, this product ticks all the right boxes. Your lawn will have a sweet, calming chamomile fragrance and geranium scent after cleaning.

As far as economies go, this is an economical choice as the product can make a 15-litre solution, which should serve your cleaning needs for a long time but if you have heavily soiled areas then you can also use neat if needed.

The dirt busters grass cleaner works well on all dog and cats wastes like urine, vomit, and poop. Once you use the cleaning solution, it keeps on neutralizing scents long after the cleaning has been done. This gives you more time before you have to clean again and also discourages repeat markings by pets.

In case you have little ones in the house, then you can relax, knowing that this neutralizer is safe for pets and kids.

Dirtbursters pet artificial grass cleaner is also designed to treat any mould growing on damp surfaces. Moss and mildew can harm not only you but also your pets, which make cleaning it before it gets worse crucial, also the longer you leave it the more it spreads, teh harder it becomes to remove and treat. The good news is that you do not need to clean the moss and mildew out again because the formula has compounds that restrict their re-growth.  

This is a strong cleaner tough on odors and stains but perfectly safe solutions that give a professional finish.

Cleaning with this solution is easy; you will need to use a pump spray or watering can for diluting the solution and spraying it on. We recommend using a sprayer as using a watering can is a little wasteful or a lot depending on how you look at it.  Depending on how bad the area has been soiled, you can use the product without diluting for badly soiled lawn areas. For better results, you can use a brush to scrub the grass and leave it to soak for up to twenty minutes before rinsing off.


  • It does a great job removing odour, stains, mildew and moss
  • Specially formulated for artificial grass
  • It is highly effective on both dog and cat urine
  • The product is safe for children and dogs
  • Multifunctional, this neutralizer cleans and deodorizes as well


  • It’s a bit expensive.

Why do we recommend it?

This product is easy to use and is highly effective. Your artificial grass will be looking and smelling fresh for a long time after cleaning. This makes it one of the best pet urine neutralizers for artificial lawns you will find on the market currently.

You will also have an easy time applying the product and rinsing it as you can decide what concentration you would like to work with depending on the intensity of the soiling.

Many reviews testify to the high effectiveness of this neutralizer, which is reassuring. Because it works on urine, poop, mold, and mildew you do not have to buy multiple products to take care of different problems. You are covered fully with this one cleaner.

We also like that this neutralizer does not only clean but that it also deodorizes and leaves the surfaces it’s used on smelling great.

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6. Simple Solution Patio & Decking Pet Stain and Odour Remover

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Simple Solution Patio & Decking Pet Stain and Odour Remover

If you have a decking or patio that has stains from pet waste, then this is just the product for you. The product uses enzymes that work to remove stains from dirty surfaces. As some pets make a habit of repeat marking where they make a mess, this solution discourages the pet from repeating the mess by completely eradicating the odor, so that the pet cannot trace the scent.

This product has incredible versatility as you can use it on carpets, beddings, clothes, and any other surfaces that are safe for water cleaning. Unlike other strong cleaning products, this neutralizer is safe to use around children and pets.

If you are concerned about keeping the environment clean, this product is manufactured using environmentally friendly ingredients from home, it cannot get any safer and sustainable. It’s also important to note that this product is safe to use around plants and real grass which is important as many people will experience runoff from the treated surface onto their lawn or garden beds. Some products will kill grass so it’s always important to check if you’re treating an area next to plants and grass.


  • It works on a variety of surfaces in your garden
  • Environment friendly so will not harm grass or plants
  • Safe to use around children and dogs
  • Easy to use, simply apply with a watering can
  • It does a good cleaning job

Why do we recommend it?

This product not only does an excellent job cleaning, but it also aids in behavioral training and housebreaking your pets. It is environment friendly, child, and pet safe. Also, it uses pro-bacteria to break up odors and stains, therefore treating the problem at the source instead of masking it.

You can use this product on many varying surfaces, from concrete to Indian stone, decking and even garden furniture if your pets spray up it. We love that is also safe to use around plants and real grass as not all pet urine neutralizers are. If you want a pet urine neutralizer for outdoors, this is well with considering.

Buyer’s guide

There are numerous products on the market marketed as pet urine neutralizers, but not all of them work as you would expect them to. If you are looking for the best functional dog urine neutralizer, here is what you should look for.

Active ingredients

The most effective neutralizers have active ingredients that break down odours and stains from the source instead of masking them. These active ingredients include enzymes of pro-bacteria that help breakdown stains and pet waste effectively. As a result, they clean a lot more effectively. If you are house training your dog and want to discourage repeat markings, this is very crucial for the training process.

When you are buying a urine neutralizer, look for one with natural organic ingredients like plants essential oils, as opposed to artificial chemicals. These are always the safest option you will use in your home.


When you are buying a urine neutralizer, you must make sure it is safe for use around the house, for both humans and pets, especially if you have small kids. Make sure that your dog does not get some kind of reaction when you use the neutralizer to clean after them.


Some neutralizers are only meant to clean pet messes. Other neutralizers can be used to clean virtually anything that you can clean with water around your house. These are always good, as it means you will not need to get different cleaning agents to use around your home.

Some neutralizers will work great on dog pee and not be very effective on cat pee. If you have both these pets in your home, you might want to get a neutralizer that can clean messes for both.

How easy is it to use?

When you are house training a pet, cleaning after them is tedious enough. The last thing you need is a neutralizer that adds to the headache. You need something easy to apply. Some neutralizers come with spray bottles. This makes cleaning a lot easier. if you buy a concentrate then you will need a sprayer and be prepared to mix the concentrate with water at the recommended ratios.


Some neutralizers are just meant to do that, neutralize. Some urine neutralizers, however, go the extra mile by incorporating other cleaning functions like sanitizing and deodorizing, such that at the end of the process, the neutralizer has broken down ordos, killed pathogenic bacterial, and deodorized the surface, leaving a pleasant scent behind. These are the ones we recommend, cheaper products often just mask the smell.

In conclusion,

If you have a pet in your house, a urine neutralizer is an essential pet product you cannot afford to skip on. You might have house trained your dog already, but occasional accidents are inevitable. This is where a neutralizer comes in handy.

If you are looking for the best functional one on the market, go check out Simple Solution Extreme Pet Stain and Odour Remover, which is our best pick. It’s very efficient when it comes to cleaning vomit, urine, or dog poop. Its strong formula contains pro-bacteria and enzymes that break down ordos and stains at the source. It comes in a multifunctional sprayer bottle with which you can either spray or use the foam or stream method of application.

Our runner-up, on the other hand, is a great alternative if you are long for a neutralizer that goes a long way without costing you a lot but you need to be prepared to mix it yourself. It has a concentrated formula, which means you use just a little. It’s also one of the best pet urine neutralizers for carpets and is perfect for indoor and outdoor use so is truly multifunctional. It is multi-functional, which means it sanitizes, deodorizes, as well as neutralizes.

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